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The vaccine expires reason [2007-3-6]
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After some dog dog injection vaccine, caught should originally in immunity scope disease.We are unable to restrain to have to ask that,“Vaccine unsafe?”Therefore some people even the regret belt dog dog injection vaccine, has each kind of wrong guess.
The massive research and the clinical practice result proved that, the injection vaccine indeed is prevents the dog dog infectious disease easy to do method.But, from the vaccine protection ratio, the domestically produced seedling also only then 85%, but imports the seedling to be able to achieve above 95%, by no means 100% absolutely insurances.The influence vaccine effect factor are very many, grasps these knowledge, is helpful in further enhances the vaccine the protective function.
One. Immune body insufficiency.Whether after the injection vaccine prevents disease, whether is decided stimulates the dog dog in the vaccine to produce the immune body, as well as immune body how many (expresses with titer).Believed generally, when the blood serum immune body titer is bigger than each milliliter 10 international units, can prevent the infectious disease.Some 30% dog injection vaccine 1 month appears the immune body approximately, completes the entire journey to inject for 1 month, the immune body achieves the maximum level.Before therefore, in completes injects completely, the immune body has not produced when or the titer quite is low, still has the infection disease possibility.In this period of time, dog dogs still must do without fail to other close preventive measure.
According to the research, the dog dog has the immune body titer height to the vaccine to be possible to divide into four groups:
1. does not have the response group, the composition injection number 5%.The dog dog possibly inherits the factor to the vaccine non-response most primary cause.The injection vaccine has the immune body ability is byⅡThe main organization compatible complex (MHC) control, belongs to the dominant heredity.
2. low response groups.After the injection vaccine has the blood serum immune body titer to be smaller than each milliliter 10 international units, composition injection number 10%.This with the heredity, the age big, obese, factors and so on immunosuppression, immunity tolerance concerns.
In 3. responds the group.After the injection vaccine has the blood serum immune body titer for each milliliter 10~100 international units, composition injection number 65%.
4. high response groups.The blood serum immune body titer is bigger than each milliliter 100 international units, composition injection number 20%.
Attention! Did not have the response group and the low response group's dog dog still has the possibility after the injection vaccine the infectious disease.
Two. Already infected the virus.Even if in front of the injection vaccine dog's has made the inspection for the dog, each target is normal, still had the possibility because of to be in the morbidity the incubation period not to be able to inspect.The vaccine produces the immune body is only effective to in the blood virus, to already entered the cell the virus to be invalid.Therefore, if in front of the injection vaccine already infected the virus, then the injection vaccine is invalid.
Three. Preserves improper.The vaccine freezes not suitably, freezes may destroy its structure.37℃ the preservation surpasses not suitably for 1 month, 4℃ the preservation surpasses not suitably for 1 year.The retention time has grown, the immunity effect can reduce.Home use refrigerator cold-storageroom preservation then.
Four. Uses improper.Vaccine not suitably in buttocks injection.The buttocks fatty tissue are many, the immune competent cell are few, after the injection produces the immune body titer is low, the immune body rate of descent is quick.
Five. Virus's variation.Even if the injection vaccine has produced the high titer immune body, the minority dog dog still had the possibility which got sick.This is because the virus may have the variation, but the existing vaccine aims at the normal virus.If the viral surface antigen has had the sudden change, the injection vaccine dog dog infected this kind of variation virus unfortunately, still had the possibility to get sick.
Six. The state of health is not good.For example the parasite elimination clean, has not had the high fever and so on, creates the immunity defeat.
Seven. The injection opportunity is not right.Is mostly too early, when divides and hyphenates a word at the end of a line the immune body very are also many injects, part of antigen are counterbalanced, certainly can produce the function greatly sells at a discount.Or has not obeyed doctor to exhort makes up strongly 11 surpasses above for a year still not to supplement, certainly still had the possibility infection, because the vaccine effect only could maintain for a year.
Eight. The individual dog itself immune system is not only perfect.
Nine. Has other is using time certain medicines.The immunity is the dog dog health basic guarantee, also is each dog host's basic duty.Also should not think has hit the vaccine on all is well with everything, after should not because the immunity the infectious disease, simply has not hit the vaccine to the dog.After completes the vaccine to be supposed to carry on the complete set inspection.If has not produced the immune body, but also should vaccinate the vaccine. |
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